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After weight loss, basal metabolic rate drops, hunger hormones increase, and you become more efficient at storing adipose tissue which gives you a higher chance of surviving famine

In addition, this study included patients (N=117) with more severe hyperglycemia (A1C greater than 11% or blood glucose greater than 280 mg/dL) who were treated with twice daily open-label Januvia 50 mg and metformin 1000 mg

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