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In addition, the inner-mitochondrial-membrane enzyme dihydroorotate dehydrogenase (DHODH) transfers electrons derived from pyrimidine synthesis to ubiquinone, reducing it to ubiquinol and thereby suppressing ferroptosis in parallel with mitochondrial GPX4 (Mao et al., 2021)

It works primarily by targeting Nicotinamide N-methyltransferase (NNMT) , an enzyme involved in metabolism, fat storage, and cellular energy balance

In vitro experiments showed enhanced antibacterial effects against drug-resistant Listeria monocytogenes (LM) when treated with anti-STR-CO-GNSs and laser irradiation

IL-23/IL-17 axis in inflammatory rheumatic diseases