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Description

Consequently, many central nervous system (CNS) disorders (including depression, schizophrenia, chronic pain, and epilepsy) are difficult to treat with small molecule pharmaceuticals 1

Instead, they target the receptors responsible for the physiological processes of growth hormone release

The fact that retatrutide passed its Phase 1 and Phase 2 trials means researchers deemed it safe enough for large-scale human testing

Additional information Peer review information Nature Communications thanks the anonymous reviewer(s) for their contribution to the peer review of this work