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Patients should contact their GP within a few days if they experience persistent symptoms that, whilst less acute, may indicate liver dysfunction: Ongoing fatigue or weakness that interferes with daily activities Loss of appetite extending beyond the expected appetite suppression from the medication Persistent nausea or vomiting that prevents adequate nutrition or hydration New or worsening abdominal swelling It is important to distinguish between expected side effects and potential liver problems

Scientists are investigating ways to improve the safety of semaglutide and reduce the risk of kidney infections

Many PlexusDx patients find that eating a balanced meal 34 hours before injection day, then staying hydrated with water or electrolyte drinks afterward, creates the smoothest transition into their treatment week

Patients might experience liver issues that require dosage changes or, in severe cases stopping the medication altogether