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These interactions make DSIP a promising candidate for research on chronic pain and the mechanisms of dependence.DSIP and opioids, 1984, PMID 6548970

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Pharmacokinetic studies conducted at Washington State University demonstrated that dihexa achieves peak plasma concentration within 30 to 60 minutes of subcutaneous administration, followed by logarithmic decay with a calculated half life of 2.5 hours in rodent models