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Adverse Event Recording If a procedure is scheduled after the patient enters the clinical trial due to aggravation of the underlying condition then the underlying condition is recorded under medical history the aggravation is recorded as an (S)AE, the procedures is treatment of the (S)AE

Oral GLP-1 formulations represent a newer category that has gained attention in recent years

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Moreover, neuroimaging can be useful to determine whether antidiabetic drugs can cross the blood-brain barrier and how they influence insulin resistance in the brain