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Ischemia-reperfusion injury-activated mitophagy establishes a positive feedback loop involving apoptosis with proteins such as MEG3, which aggravates acute kidney injury that is secondary to ischemia-reperfusion injury [235]

Enterobacteriaceae: disruptive microbe Enterobacteriaceae are a family of bacteria that can become problematic when overgrown

This allows for the specific delivery of therapeutic agents to key cell types involved in disease progression, such as activated hepatic stellate cells in fibrosis, inflamed hepatocytes in NAFLD, or neoplastic cells in HCC [14]

However, excessive or abnormal melanin production can result in various hyperpigmentation disorders, such as freckles, melasma, and age spots 6