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The FDA-approved dosing schedule involves a gradual titration starting at 2.5 mg once weekly, increasing every four weeks to minimize gastrointestinal side effects while optimizing therapeutic response

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Nel trial PIONEER 4, condotto su un periodo di 26 settimane, lassunzione quotidiana di 14 mg di semaglutide orale ha determinato una riduzione media del peso corporeo di circa 4,4 kg rispetto al basale