Additionally, HT in pregnancy is increasingly recognized as a contributor to gestational diabetes mellitus and maternal metabolic dysregulation, which can have long-term consequences for both the mother and child [12, 13]
Remarkably, in a trial using high-dose thiamine for fatigue related to inflammatory bowel disease (IBD), the relative abundances of Faecalibacterium prausnitzii , a member of the Ruminococcacea family, and Roseburia hominis , a member of the Lachnospiraceae family, inversely correlate with fatigue severity both pre- and post-treatment with thiamine (62)
After supplementing with 156 mg zinc gluconate (providing 20 mg of elemental zinc) twice daily for two months, scores on a standardized assessment of the impact of tinnitus on quality of life were found to have improved significantly in 17 (85%) of participants
Plant Physiol 147:19361946 Fonseca S, Chini A, Hamberg M, Adie B, Porzel A, Kramell R, Miersch O, Wasternack C, Solano R (2009) (?)-7-iso-Jasmonoyl-L-isoleucine is the endogenous bioactive jasmonate