why is my compound tirzepatide red itchy bump on injection site : r/tirzepatidecompound Tirzepatide compound. What I learned.

Reduced food and fluid intake due to appetite suppression further decreases stool bulk and moisture, contributing to constipation

When GLP-1 binds to GLP-1R on the surface of -cells, cAMP-dependent PKA is activated and subsequently activates the downstream signal PI3K, which inhibits apoptosis in islet -cells by blocking the expression of the pro-apoptotic protein Bax (Li et al., 2021) (Figure 4)

These treatments target hormones that regulate appetite, metabolism, and insulin

Some common signals include feeling bloated after eating (especially fatty foods) or having some mild discomfort in the upper right part of their belly that comes and goes