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The researchers concluded that AOD9604 displayed a very good safety and tolerability profile indistinguishable from placebo. Critically, zero serious adverse events were attributed to the peptide, and no participants withdrew due to treatment-related effects

Because retatrutide is not currently licensed in the UK, the most important safety message is straightforward: this medication should not be self-administered outside of an approved clinical trial or a formal MHRA access scheme (such as the Early Access to Medicines Scheme [EAMS] or named-patient unlicensed supply) overseen by a qualified medical team

But combined with a GLP-1 receptor agonist it amplifies appetite suppression and adds distinct benefits through fat tissue and brain reward pathways that GLP-1 alone does not fully address

Are you using preoperative gastric ultrasound in your practice