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Kybella is currently FDA-approved to treat moderate to severe submental fat and any other area of the body is considered an off-label usage of this injection to eliminate body fat

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Since effective LDL-C reduction is the most important method to improve the prognosis in HoFH, intensive treatment should be carried out, involving all available interventions, i.e., high doses of potent statins, ezetimibe, PCSK9 inhibitors, and LDL apheresis [265, 284]