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Vitamins and excitotoxicity The dysregulation of glutamatergic-GABAergic equilibrium remains a pathophysiological cornerstone of epileptic hyperexcitability

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We dont fully understand how, but it seems like this type of B12 could modulate the synthesis of melatonin, a hormone involved in regulating your sleep-wake cycle: Eight young males were subjected to a single blind cross-over test to see the effects of vitamin B12 (methylcobalamin) on the phase-response of the circadian melatonin rhythm to a single bright light exposure

Age : In the UK and US, nearly 20% of adults over 60 have B12 deficiency