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For type 2 diabetes, however, there are multiple medication classes with different mechanisms of action, and patients are commonly on more than one simultaneously (American Diabetes Association, 2026)

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2025: Novo Nordisk announced positive Phase 3 ESSENCE trial results for semaglutide in early Alzheimer's disease, reporting statistically significant slowing of cognitive and functional decline a breakthrough data package that could establish GLP-1 therapy as a neuroprotective agent and open an addressable market of 6.5 million Alzheimer's patients in the U.S