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Description

The challenge on retatrutide is that strong appetite suppression makes it easy to under-eat, so protein usually has to be prioritized on purpose

In animal models, IBI3032 achieved five to ten times higher oral exposure at equivalent doses, with improved efficacy and good tolerability in both GLP-1R KI DIO mice and obese monkey models, achieving comparable therapeutic effects at lower doses

The Lancet , 402

However, while approved by the FDA for Type 2 diabetes under the brand name Mounjaro, tirzepatide is still in the late stages of the approval process for weight loss