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Taking a proton pump inhibitor or other medications that reduce stomach acid for reflux or ulcers, as well as taking metformin for diabetes, can reduce absorption of B12 in food or supplements

This range may be optimal, according to some research, given its association with improved cognitive function

Although Vitamin B12 is naturally found in foods such as meat, fish, dairy products and eggs, some people struggle to absorb enough from their diet due to medical conditions, digestive disorders or dietary choices

From a health economics perspective, lifelong B12 supplementation should involve cost-effective delivery routes and tailored dosages to optimise clinical outcomes while minimising excess