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Fibroblast growth factor 19 and fibroblast growth factor 21 regulation in obese diabetics, and non-alcoholic fatty liver disease after gastric bypass

Abstract Despite Polycystic Ovary Syndrome (PCOS) is a very prevalent disorder among women of reproductive age, there is widespread agreement that until now, no pharmacological options are available to tackle the entire spectrum of clinical manifestations encountered in the clinical practice

Rather than representing a purely cutaneous condition, PsO appears to be a systemic metabolicinflammatory disease in which insulin resistance, adipokine imbalance, and altered gutendocrine signaling contribute to immune dysregulation long before the onset of clinically overt joint involvement (7)

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