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Researchers at institutions including the University of Gothenburg and Scripps Research Institute showed that semaglutide and similar compounds reduce voluntary alcohol intake, decrease nicotine self-administration, diminish cocaine-seeking behavior, and prevent relapse-like drinking after periods of abstinence

With their cross-biological-system effects, GLP-1s may prove helpful in reducing the impact of some of these factors

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Common themes in user reports include unexpected disinterest in alcohol rather than active resistance, reduced tolerance requiring fewer drinks to feel effects, diminished pleasure from alcohol when consumed, and decreased frequency of alcohol-related thoughts throughout the day