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Dogs with a B12 deficiency and/or anemia may have one or more of the following symptoms: lack of energy weakness reduced interest in play loss of appetite diarrhea weight loss loss of muscle mass confusion seizures What Causes B12 Deficiency in Dogs

Out of the B12 family, only Methyl-B12 has the ability to activate the methionine/homocysteine biochemical pathway directly

Some research protocols include 500 to 1000 mg of vitamin C taken 30 to 60 minutes before exercise or peptide administration

Half-life & frequency rationale No published human pharmacokinetic study of 5-Amino-1MQ exists, and the mouse efficacy study itself did not report half-life or bioavailability figures