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The FTCs interim staff report on PBMs documented that the Big Three systematically reimburse their affiliated specialty pharmacies at rates above what they pay competing independent specialty pharmacies for identical drugs, documenting in some cases reimbursement differentials exceeding 20% for the same drug and dosage form

Patients with personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2 should not use either medication

Modified-release metformin is preferred over standard-release for tolerability and adherence

The STEP trials, which tested semaglutide for weight management, demonstrated that participants on the 2.4 mg maintenance dose lost an average of 15 percent of their baseline body weight over 68 weeks