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Human data is limited to two PK/PD studies and a discontinued Phase II trial
Increasing GSH through synthesis would also seem to be useful therapeutically but as oxidants and most electrophiles would not seem appropriate, natural compounds such as curcumin, a principal ingredient of curry powder (Dickinson et al., 2003), and sulforaphane, a potent Phase II gene-inducing compound in broccoli, (Brooks et al., 2001) have been proposed but none of these natural has actually become a major therapeutic agent
58,156,162 Future Perspectives GLP-1 RAs Currently Under Development Based on previous findings, dosages that enable longer durations and less frequent administrations have been investigated
Tesamorelin is generally well tolerated in its approved population
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