Side effects and safety profiles When considering Zepbound and Wegovy for weight loss, its essential to understand their side effects and safety profiles: Common side effects: Both medications may cause gastrointestinal issues such as nausea, diarrhea, vomiting, and constipation

On the heels of basic research on the venom of Gila monsters in the preceding decades,1 exenatide secured the first US FDA approval in the class on April 28, 2005.2 While the prominent GLP-1 brand names are household names today, the class was off to a relatively slow start at first five years passed before it reached blockbuster status (US$1 billion (770 million) in sales), and another five went by before the first formal approval of a GLP-1 drug indicated for obesity became a reality.3 Last year saw sales for the class cross $50 billion and, with another 40% in revenue growth in store for 2025, the GLP-1 segment of the pharmaceutical industry is firmly in the rapid growth phase of the market, per Investment Bank Consensus
Both are GLP-1 medications for weight management, but they work slightly differently
However, the small sample sizes in many MSC studies limit the reliability of clinical conclusions (Izadi et al