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Liraglutide is sold as Saxenda and works through the same GLP-1 receptor agonist mechanism as semaglutide and tirzepatide, mimicking GLP-1 to regulate appetite and blood sugar rather than acting on the GIP pathway that tirzepatide also targets

Written By: Anamika Koshti, PharmD Reviewed By: Pharmacally Editorial Team Eli Lilly and Company has announced positive topline results from two pivotal Phase 3 studies of retatrutide, its investigational once-weekly triple hormone receptor agonist that targets glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors

Cognitive behavioral therapy guided self-help and orlistat for the treatment of binge eating disorder: a randomized, double-blind, placebo-controlled trial