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Common side effects of taking too much include: Nausea or an upset stomach Heartburn Diarrhea A mild "fishy" body odor (this happens when the body breaks down high doses of the supplement) Additionally, recent studies highlighted by organizations like the Cleveland Clinic have noted that gut bacteria can interact with L-carnitine to produce a compound called TMAO (trimethylamine N-oxide)

There are in general three reasons for this ignorance of the prevalence of common diseases , the lack of specificity of particular drugs for particular diseases, and the lack of standardisation of therapy

You should not use Neo-B12 Injection if you: are allergic to Hydroxocobalamin or any ingredients in Neo-B12 Injection are pregnant or are breastfeeding are taking medicines that interact with Neo-B12 Injection, including oral contraceptives and the antibiotic chloramphenicol, without discussion with your doctor How should Neo-B12 Injection be taken

This means they are only associations and we have no reason to believe that a MTHFR mutation can actually cause a disease