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La ghrelina es la hormona intestinal con efecto orexgeno ms importante, cuya funcin es estimular la ingestin de alimentos y el aumento de peso, activando las neuronas orexgenas en el ncleo arcuato del hipotlamo a travs de la modulacin de la sealizacin mTORC1/S6K1 y la regulacin de las ceramidas 10,11