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Conclusion This novel study in youth with type 2 diabetes demonstrated that short-term metformin improved postprandial blood glucose levels and was associated with modest increases in incretin concentrations in the absence of changes in rates of glucose production and gluconeogenesis

GLP-1 medications like Mounjaro, Wegovy and Ozempic have become a popular tool for weight management, with an estimated 1.6 million people using them in Great Britain alone.[1] While these medications can be highly effective for supporting weight loss, theres evidence that weight regain is common after treatment stops.[2] This is because GLP-1 medications work by reducing appetite and supporting metabolic processes that make it easier to lose weight

Do not self-manage and contact your doctor if the stomach pain did not improve

The robust weight loss combined with a well-tolerated safety profile reinforces our confidence in the clinical development programme [of CT-388] as we advance to phase III trials" Dr Levi Garraway, PhD, Roches Chief Medical Officer and Head of Global Product Development, said: We are pleased to see such meaningful weight loss in people treated with CT-388