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It has been recently shown that efflux pumps in the plasma membrane of cancer cells are crucial for the extracellular efflux of anticancer drugs 134

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Exposure to ultraviolet light can trigger melanocytes in the skin to produce melanin, leading to an increased amount of pigment in the skin and an overall darker complexion as well as the potential development of sun spots, dark spots, and melasma

39,40,41 The integrin IIb 3 receptor occupies a central role in determining the extent of platelet aggregation, in part because it is present at an extraordinarily high density on the platelet surface (approximately 50,000 receptors per platelet, such that receptors are probably less than 20 nm apart)