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Using any of them without a valid prescription is illegal and carries unmonitored health risks, including cardiovascular strain, anxiety, insomnia, and dependence

Currently, there is no direct evidence that GLP-1RA use contributes to progression of pancreatic cysts to PDAC, but this remains an important knowledge gap for future investigations considering the high prevalence of pancreatic cysts in the general population (~ 10% by age 50 and ~25% by age 70) 56

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This represents a shift in clinical thinking with practical consequences