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When GLP-1s were approved for chronic weight management, the intention was for them to be used by overweight individuals at risk of other medical issues

"More studies are needed to help establish how effective these drugs are, what the long-term effects are, if some are better than others, and what dose is most effective for reducing drinking verus controlling blood glucose, for example," DiFeliceantonio said

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Weight regain is linked with feelings of shame, hopelessness, and emotional distress, self-blame, and new or worsening mental health issues, like anxiety, depression, disordered eating behaviors