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53 Therapeutic targeting of cardiac proteostasis The recognition that proteostasis failure contributes directly to cardiovascular disease has accelerated the development of therapeutic strategies aimed at restoring protein quality control rather than targeting isolated downstream manifestations

Importantly, SFN also enhances the ROS levels in lymphocytes within whole blood of RA (rheumatoid arthritis) patients and inhibited the production of pro-inflammatory TH17 related cytokines

But, these studies are pretty short term, lasting less three months