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The FDA recommends semaglutide for weight loss if you meet one of the following criteria: Have a body mass index (BMI) of 27kg/m2 or greater and at least one weight-related condition, such as high blood pressure, Type 2 diabetes or high cholesterol Have a BMI of 30kg/m2 or greater Avoid semaglutide if you have: History of medullary thyroid cancer History of gallbladder disease History of pancreatitis Multiple endocrine neoplasia syndrome type 2 (MEN2) Conclusion: Semaglutide for Weight Loss Semaglutides effectiveness in reducing body fat can be attributed to its impact on appetite regulation, gastric emptying, and energy expenditure

One is that when glucose levels are high, they trigger the pancreas to release insulin and suppress glucagon, which helps lower your blood sugar levels

doi:10.1186/s12891-017-1571-8 , 11 Schneider B, Varghis N, Kennedy DJ

Its first generic from Indias Natco Pharma was approved in 2022 and is waiting for the drug patent expiration of Revlimid in 2025