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Megaloblastic anemia Diminished activity of methionine synthase in vitamin B 12 deficiency inhibits the regeneration of tetrahydrofolate (THF) and traps folate in a form that is not usable by the body ( Figure 3 ), resulting in symptoms of folate deficiency even in the presence of adequate folate

Colorimetric/fluorometric assay kits [Biovision Incorporated, Milpitas, USA] were used to measure aspartate aminotransferase (AST), alanine aminotransferase (ALT) and -glutamyltransferase (-GGT)

While the exact cause of vitiligo is still unknown, researchers believe that vitiligo causes involve a combination of genetic predisposition, environmental triggers, and autoimmune factors which ultimately cause the destruction of melanocytes the cells responsible for producing melanin which give skin its color

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