Also in kidney, localization of GLP-1 receptor is under investigation, but it is thought to be expressed in vascular smooth muscle cells and immune cells in kidney [43]
However, because most palmar and plantar pigmentation is completely benign, counseling of patients to provide reassurance and education is key
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The protein/ligand visualized 12 hydrogen bond formation with the amino acids ALA 146, ASP 156, PHE 157, SER 160, SER 162, TYR 165, GLU 177, GLN 228, ASN 229, HIS 248, VAL 292, and GLU 295