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Glutathione and Immune Modulation Depleted intracellular glutathione has been associated with shifts in T-helper cell balance, specifically a Th1/Th2 imbalance, and increased pro-inflammatory cytokine signalling, including elevated tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6)

All these results show how the different active components of grape juice can act differently from RESV to exert a beneficial effect in the treatment of PE [37]

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It occurs naturally in human plasma, saliva, and urine, and its plasma concentration declines significantly with age, from approximately 200 ng/mL in young adults to much lower levels in older individuals