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Quality assessment Risk of bias (RoB) assessment was performed independently by 2 reviewers (W.W., Y.-S.L.) using the Cochrane Risk of Bias Assessment tool, and disagreements were resolved by discussion [8]

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Secondary plots for the rate constants of the rapid first reaction phase at variable PfGrx concentrations deviated from linearity and showed a hyperbolic correlation at millimolar GSH concentrations (Fig