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doi: 10.3390/cancers13143466

Lipodystrophy includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue) and may affect insulin absorption [see DOSAGE AND ADMINISTRATION ]

MET activation is thus involved in brain plasticity, as suggested by the fact that HGF administration on hippocampal slices enhances the phosphorylation of the glutamatergic NMDA receptor subunit GluN1, augments the NMDA-mediated currents, and increases the amplitude of long-term potentiation (LTP) induced by elevated neuronal activity (Kato et al., 2012)