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Self-assembled copper-amino acid nanoparticles for in situ glutathione AND H2O2 sequentially triggered chemodynamic therapy

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j-o , Serum and tumor metabolites from mice with orthotopically implanted HCC-1806 cells treated with the vehicle, n-acetylcysteine (30 mM in the drinking water), GGsTop (189 M in the drinking water), or NAC and GGsTop (Tumors

The primary structural modification confers a longer half-life compared to HGH Fragment 176-191, which in pharmacokinetic terms suggests extended activity duration and potentially reduced dosing frequency in experimental models