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Nausea - the most common side effect, reported more frequently at higher doses Diarrhoea Vomiting Constipation Abdominal pain or discomfort These side effects were generally mild to moderate in severity and were most common during the dose escalation period (the first 1216 weeks of treatment, when the dose is gradually increased)

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and mitochondrial intermediate peptidase, which was increased 1.57-fold (p=0.028) and is thought to be involved in maturation of the oxidative phosphorylation complexes

FDA Compounding and the FDA: Questions and AnswersExplains that compounded drugs are not FDA-reviewed for safety, effectiveness or quality before dispensing, and the 503A/503B framework