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Suspension nasal sprays require all of the same device performance tests as solution sprays, plus drug particle size distribution (DPSD) by cascade impactor because it is the drug particle size (not the droplet size) that determines absorption rate in the nasal mucosa for suspensions
The Shoemaker Protocol is officially part of the Bredesen Protocol as is key in establishing the level of neurologic harm associated with biotoxins
Pulmonary fibrosis, an irreversible and progressive lung disease, lacks effective treatments
Thus dosage, pharmacokinetics, long-term safety, off-target effects in humans remain unknown
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