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Annals of the Academy of Medicine, Singapore, 53 (4), 241252

The ternary complex itself acts as a guanine nucleotide ex-change factor (GEF), such that the GEF activity of GPCR/G protein complex promotes the GDP/GTP exchange in G protein [5, 6], which in turn decompose the G protein into G and G subunits and releases them into cellular milieu

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View Study Oesser S, Adam M, Babel W, Seifert J