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NR has shown particular promise in improving mitochondrial function and enhancing cellular resistance to oxidative stress

Preclinical studies show it enhances insulin sensitivity, promotes fat oxidation, improves exercise capacity, and counters age-related metabolic decline [1] [4]

Therefore, the ferroptosis pathway shows great potential as a target in the treatment of drug-resistant tumors, ischemic organ injury and neurodegenerative diseases, and inducing or inhibiting ferroptosis has become a new strategy to treat human diseases