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For Alzheimers disease, researchers gave 204 participants with mild to moderate disease liraglutide (a GLP-1 that pre-dated Ozempic) and measured how much brain volume they lost

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Activation of these receptors in the brain (particularly brainstem and hypothalamic regions) suppresses appetite, reduces food intake through both homeostatic and hedonic pathways, slows gastric emptying to prolong fullness, and inhibits postprandial glucagon release to aid glucose control