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For best results, consider: Following a balanced diet focused on whole foods, lean proteins, and smaller amounts of healthy fats and complex carbs Practicing portion control, which becomes easier as tirzepatide reduces appetite Getting enough nutrition, even with a reduced appetite Doing regular physical activity, including both cardio and strength training Staying well hydrated Getting quality sleep Managing stress through mindfulness practices A registered weight loss dietitian who specializes in weight management can help you manage your diet on tirzepatide