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RNAi therapeutics: principles, prospects and challenges

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In the GLP-1 RA vs SGLT-2 inhibitor cohort, there was no difference in the adjusted HR of suicide or suicide attempts between patients treated with GLP-1 RAs compared with patients treated with SGLT-2 inhibitors after 1 year of follow-up (HR 365 0.93 [0.57;1.52]), see Table 2

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2) The research team of Wekwejt et al employed zebrafish, specifically 3-5 month old longfin phenotype individuals, as a model to investigate the impact of a short-term high-fat (HF) diet on neurobehavioral outcomes and the potential ameliorating effects of MT-II

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If it is an oral supplement, treat the weight loss claims with healthy scepticism and look for independent, peer-reviewed evidence rather than manufacturer claims

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