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In another study, genotyping by multiplex PCR of GST-M1 and GST-T1 in 101 Egyptian women with nonsegmental vitiligo vulgaris and 101 age female healthy matched controls show that the absence of GST-M1 gene and the presence of the GST-M1/GST-T1 double-null genotype represent a risk factor for vitiligo in these women ( p = 0.01

One MRS study found reduced glutathione in the medial prefrontal cortex (mPFC) in schizophrenia patients compared with healthy controls [21]

However, it is quickly broken down by other atmospheric reactions, so it does not accumulate in large quantities

The key clinical question is whether the pituitary is the bottleneck