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GhezzoAViscontiPAbruzzoPMBolottaAFerreriCGobbiGet al
The excellent antioxidant activity of quercetin is exerted primarily through effects on glutathione, enzyme and reactive oxygen species (ROS) activity and by regulating signal transduction pathways such as heme-related factor oxygenase 1/nuclear factor erythroid 2 (Nrf2), mitogen-activated protein kinase, toll-like receptor 4/phosphatidylinositol-3-kinase, and adenosine monophosphate 5-activated protein kinase
Once the acute group was excluded from analysis, the LC group displayed a more distinct metabolome profile compared to the HC and R groups ( Figures 2C, D )
Cell 2 , 10531060 (2003)
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