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In a clinical trial of more than 3,000 adults with obesity, participants who received the highest dose of orforglipron, 36 milligrams, lost 11.2% of their body weight -- about 25 pounds on average -- over more than 16 months

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Key Takeaways GLP-1 medications work best when paired with a diet that enhances their appetite-suppressing effects Incorporating protein-rich and fibre-laden foods can optimise fat loss and muscle maintenance Avoiding sugar-laden and high-glycaemic foods is crucial for minimising side effects and maintaining stable blood sugar levels A balanced nutrient intake prevents deficiencies and supports overall health during weight loss Practical tips for social situations and dining out can help you stick to your diet without feeling restricted What is GLP-1

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