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Compounded medicine is an important safety valve for shortages, but the FDA does not guarantee it is safe or effective and facilities that make compounded medicines, such as 503B outsourcing facilities, dont have to be inspected by the FDA before shipping products

This time, however, we used gld-1(q361) , a missense mutant that abrogates GLD-1 protein function but produces detectable gld-1 mRNA and GLD-1 protein [30, 45, 46] ( Fig 6A )