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Does the mechanistic rationale for SS-31 translate into measurable benefits

References 1 MirbagheriMAdibniaVHughesBRWaldmanSDBanquyXHwangDK

Timing for chronic muscle remodeling and endurance effects To try to raise muscle carnitine content, the human protocols that succeeded typically used daily supplementation for 12 weeks or longer, usually around 2 grams per day

Research models with baseline HbA1c above 6.0% or fasting glucose above 110 mg/dL should not initiate this protocol without continuous glucose monitoring, as MK-677 specifically has been shown to increase fasting glucose by 58 mg/dL and HbA1c by 0.30.5% even in metabolically healthy subjects