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They are marked in Units on the insulin syringe barrel (see illustration)

If it's been at room temperature for multiple days, discard and open a fresh vial

There is some new research suggesting that the crystals stimulate an inflammatory response, and that some of the pain is mediated by the formation of new blood vessels and nerves that develop in the tendon tissue affected by the crystal formation(2)

Inflammation and retinal disease: complement biology and pathology 105125 Vabulas RM et al (2002) HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway